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Viral Integration Site DataBase
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TVIS30002978
Basic Information
VIS ID
TVIS30002978
Fusion event
HIV-RFX1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14081648/13970836 (Hg38)
End
14081648/13970836 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
RFX1
miRNAs that regulate target gene
hsa-mir-197-3p
;
hsa-mir-346
;
hsa-mir-124-3p
;
hsa-mir-3978
;
hsa-mir-92a-1-5p
;
hsa-mir-3148
;
hsa-mir-6124
;
hsa-mir-8069
;
hsa-mir-758-5p
;
hsa-mir-15a-3p
;
hsa-mir-4753-5p
;
hsa-mir-548as-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-4776-3p
;
hsa-mir-578
;
hsa-mir-587
;
hsa-mir-4659b-5p
;
hsa-mir-4659a-5p
;
hsa-mir-6801-5p
;
hsa-mir-5590-5p
;
hsa-mir-153-5p
;
hsa-mir-10b-3p
;
hsa-mir-6826-5p
;
hsa-mir-370-5p
Nearest miRNA
hsa-mir-10395/Upstream/95825; hsa-let-7e/Downstream/102525;
Nearest TSS
ENST00000633603/Upstream/6781;
ENST00000622575/Downstream/35426;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/6824
,
chr19-CpG: 147/Downstream/34884
Upstream sequence
tttgggaggccaaggcaggtgggtggatcatgagatcaggagactgagaccagcctggtcaatattgtgaaaccccgtctctactaaaaatacaaaaatt
Downstream sequence
agctgggagtggcggtgtgcgcctgtagtcccagctgcttgggaggctgagacaggagaatcatttgaacttgggaggcagaggttgcagggaggcagag
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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