Basic Information
VIS ID
TVIS30003002
Fusion event
HIV-IL12RB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
18184368/18073558 (Hg38)
End
18184368/18073558 (Hg38)
Orient
-
Location type
Exonic
Fragile sites / regions
FRA19B
Target gene
IL12RB1
Nearest miRNA
hsa-mir-10395/Upstream/2623950; hsa-let-7e/Downstream/208519;
Nearest TSS
ENST00000633603/Upstream/64009; ENST00000601226/Downstream/13372;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/21352, chr19-CpG: 36/Downstream/24053
Upstream sequence
cttttgcctcctgctccccatcccaggccacCCCACAGCCCTGTGACAGCCCCGTTACCTGCTCTTTCAGGGTCAGCCGCCTCCTCCCATCCTGGCCCAG
Downstream sequence
CTGCTCCACCGAGAATCTCACCTGAGGCTGTGGGGGGTTTTCTGCAATCAGAACCAAACCAACTAGACGAATTGGAAGGAGAGAAAGACTGATGGATGTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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