Basic Information
VIS ID
TVIS30003008
Fusion event
HIV-PBX4 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
19715585/19604776 (Hg38)
End
19715585/19604776 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
PBX4
miRNAs that regulate target gene
hsa-mir-1274a
Nearest miRNA
hsa-mir-10395/Upstream/169618; hsa-let-7e/Downstream/794496;
Nearest TSS
ENST00000633603/Upstream/24822; ENST00000559614/Downstream/1574;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/58767, chr19-CpG: 60/Downstream/13542
Upstream sequence
tgcaacctccacctcccaggttcaagtgattctcctgcctcagcctcctgagtagctggaactataggcgcgtgccaccacactcagctaattttttatg
Downstream sequence
tttttagtatagacagggtttcatggtattagccaggatggtctcgatctcctgacctcatgatccacttgcctcggcctcccaaagtgctgggatcaca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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