Basic Information
VIS ID
TVIS30003018
Fusion event
HIV-DPY19L3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
32904844/32413938 (Hg38)
End
32904844/32413938 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
DPY19L3
miRNAs that regulate target gene
hsa-mir-27a-3p ; hsa-mir-6721-5p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-191-3p ; hsa-mir-6757-3p ; hsa-mir-3121-3p ; hsa-mir-6773-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-6748-3p ; hsa-mir-483-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-1299 ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3190-3p ; hsa-mir-3202 ; hsa-mir-378a-3p ; hsa-mir-378b ; hsa-mir-378c ; hsa-mir-378d ; hsa-mir-378e ; hsa-mir-378f ; hsa-mir-378h ; hsa-mir-378i ; hsa-mir-422a ; hsa-mir-4470 ; hsa-mir-4520-3p ; hsa-mir-4533 ; hsa-mir-4638-3p ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-5706
Nearest miRNA
hsa-mir-10395/Upstream/12014584; hsa-let-7e/Downstream/2708762;
Nearest TSS
ENST00000633603/Upstream/7749; ENST00000585597/Downstream/25041;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/7611, chr19-CpG: 99/Downstream/167031
Upstream sequence
ccttagcctcccgagtagctgggaccacaggtgcacgtcactgttcccagctaattatttaattttttgtagagatgggcctactatgttgcccaggctg
Downstream sequence
ttctcaaactcctggactcaagcaatcctcctgcgttggcctcccaaaatattgggattataggtgtgagccgctatgcccACCTATCTCTTTAAAATGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate