Basic Information
VIS ID
TVIS30003150
Fusion event
HIV-PUS10 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
61217594/60990459 (Hg38)
End
61217594/60990459 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
PUS10
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1208 ; hsa-mir-1307-3p ; hsa-mir-143-5p ; hsa-mir-216b-3p ; hsa-mir-342-3p ; hsa-mir-3622b-5p ; hsa-mir-367-5p ; hsa-mir-4423-5p ; hsa-mir-4638-5p ; hsa-mir-4695-3p ; hsa-mir-5586-3p ; hsa-mir-5693 ; hsa-mir-6499-3p ; hsa-mir-6501-5p ; hsa-mir-744-3p ; hsa-mir-7641
Nearest miRNA
hsa-mir-1301/Upstream/603014; hsa-mir-10b/Downstream/1215367;
Nearest TSS
ENST00000437798/Upstream/96062; ENST00000444100/Downstream/26734;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/108578, chr2-CpG: 89/Downstream/75274
Upstream sequence
agttacagggccaaaattcagaagaagggaaccaaagatgagccaggtgttttgagcagcttttccctaaggggcatctgttgtcagaagagagagaggg
Downstream sequence
aatcctgataagccctatgttttggctgaaaccatgaagcatgacaccctagaagcaggggtaaatggggacgagaacagtccttaaaggtgttaaagat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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