Basic Information
VIS ID
TVIS30003165
Fusion event
HIV-KANSL3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
97292847/96627110 (Hg38)
End
97292847/96627110 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
KANSL3
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-877-3p ; hsa-mir-93-3p ; hsa-mir-484 ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-3156-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-188-3p ; hsa-mir-4301 ; hsa-mir-4705 ; hsa-mir-6500-3p ; hsa-mir-141-5p ; hsa-mir-196a-3p ; hsa-mir-7106-3p ; hsa-mir-3128 ; hsa-mir-150-5p ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-1273g-3p ; hsa-mir-21-5p ; hsa-mir-3200-5p ; hsa-mir-4539 ; hsa-mir-4754 ; hsa-mir-590-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/7814656; hsa-mir-10b/Downstream/171168;
Nearest TSS
ENST00000437798/Upstream/7348; ENST00000505256/Downstream/4374;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/76622, chr2-CpG: 54/Downstream/11092
Upstream sequence
tattaatttttttgcaactatttaaaaatgtaaaaatcattccacacaaaaacaagcaatgggccaaatttaaatcagcccactgtcatagttagacaac
Downstream sequence
cactAATGCAGACAATTAAATAAGGTAGTAATATTTAAACCATTTCACAAAATATCAGCCATTAATAAAGAAAGCCAGAGTCAGGGGCAGGGAAGGGAGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate