Basic Information
VIS ID
TVIS30003174
Fusion event
HIV-ZC3H6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
113074711/112317134 (Hg38)
End
113074711/112317134 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
ZC3H6
miRNAs that regulate target gene
hsa-mir-6516-5p ; hsa-mir-1273e ; hsa-mir-455-3p ; hsa-mir-6499-3p ; hsa-mir-4722-5p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-4768-3p ; hsa-mir-4649-3p ; hsa-mir-4257 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-6806-5p ; hsa-mir-330-3p ; hsa-mir-3142 ; hsa-mir-1245b-5p ; hsa-mir-6871-3p ; hsa-mir-1183 ; hsa-mir-6835-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-4789-5p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-5580-3p ; hsa-mir-4789-3p ; hsa-mir-8485
Nearest miRNA
hsa-mir-1285-2/Upstream/546000; hsa-mir-10b/Downstream/1265825;
Nearest TSS
ENST00000437798/Upstream/17278; ENST00000502881/Downstream/15008;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/40754, chr2-CpG: 129/Downstream/115404
Upstream sequence
CATCCACTGTCTTGGGCAGGAATTCTAAGGGGTCATTTGAGTTATTATTTGTTCATTATTAAAGACTGAAGATAATGACCATAATTTTACCATGAGACAC
Downstream sequence
CATGTAGAAAATTCAGCTGTTGTTTCTTTGTTTCTCATTGTTTCTTACCtttttttcttttttcttttttttttttttGTGAATAGGGAGATCAGTGTAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate