Basic Information
VIS ID
TVIS30003176
Fusion event
HIV-ACTR3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
114671150/113913573 (Hg38)
End
114671150/113913573 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2B
Target gene
ACTR3
miRNAs that regulate target gene
hsa-mir-124-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/192205; hsa-mir-10b/Downstream/13509964;
Nearest TSS
ENST00000437798/Upstream/22975; ENST00000489779/Downstream/13796;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/22838, chr2-CpG: 92/Downstream/65703
Upstream sequence
AATGAAACAGTACCCCAATTTTTAGGGTGATATTGCAGTTAACAGTATGGGGGTATAACTAATTATCAAGTAGTCCATTCCCCATCATATACCTATGAAG
Downstream sequence
ACTGTCCTTTGGTTTGTGGATATGACTACTGTTTGTAGGGCCCGTATCTGTTGACGTCCTCACTAAGTGCCCATGTTTCAAAATATGGATGGAAGGACAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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