Basic Information
VIS ID
TVIS30003179
Fusion event
HIV-AMMECR1L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
128640029/127882455 (Hg38)
End
128640029/127882455 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
AMMECR1L
miRNAs that regulate target gene
hsa-mir-101-3p ; hsa-mir-877-3p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-15b-5p ; hsa-mir-221-3p ; hsa-mir-10a-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-548aw ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-2355-5p ; hsa-mir-29a-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-6505-3p ; hsa-mir-581 ; hsa-mir-6840-3p ; hsa-mir-500b-3p ; hsa-mir-8083 ; hsa-mir-7161-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-182-5p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-191-5p ; hsa-mir-196a-3p ; hsa-mir-3612 ; hsa-mir-4771 ; hsa-mir-499b-5p ; hsa-mir-621 ; hsa-mir-650 ; hsa-mir-6511a-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/458837; hsa-mir-10b/Downstream/3608705;
Nearest TSS
ENST00000437798/Upstream/24298; ENST00000609350/Downstream/2405;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/24025, chr2-CpG: 124/Downstream/3071
Upstream sequence
TGACACAGAGTTGACTTGAAATTCAATTTAATAATTACATTATGGGTACTGAAATGGCACCTGAGCTATAATTCTGTCCTACTTATGGAACTATTCCAGG
Downstream sequence
AAACAGTCAGAAAAACCCACATACATTCTGGTAACCATACCAAATAATCATTTATTTTTGAAACCCCCATCATACACACATCCAAAACATTTGGTGTGTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate