Basic Information
VIS ID
TVIS30003211
Fusion event
HIV-STAT1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
191875075/191010349 (Hg38)
End
191875075/191010349 (Hg38)
Orient
-
Location type
Intronic
Target gene
STAT1
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-146a-5p ; hsa-mir-34a-5p ; hsa-mir-615-3p ; hsa-mir-653-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-4693-5p ; hsa-mir-5009-3p ; hsa-mir-501-5p ; hsa-mir-1183 ; hsa-mir-500a-5p ; hsa-mir-605-5p ; hsa-mir-140-5p ; hsa-mir-150-5p ; hsa-mir-223-3p ; hsa-mir-203a-3p ; hsa-mir-450a-5p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-10b/Upstream/1877238; hsa-mir-1244-1/Downstream/15772885;
Nearest TSS
ENST00000437798/Upstream/26635; ENST00000431351/Downstream/3606;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/128476, chr2-CpG: 70/Downstream/3533
Nearest cancer related gene
STAT1(TSG, No orient, 0)
Upstream sequence
ggcagccttctctggcctcttttatttaaactgcaaccacctcccaccctggaaacatgctctctcttttccctggtttatttttcttcatagtacttac
Downstream sequence
accaccatctgacctaccacatattttattttcattattgtctgttttcaccacttgaagggatggatgttggtggaggattctgtgcactggtgtatcc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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