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VISDB
Viral Integration Site DataBase
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TVIS30003222
Basic Information
VIS ID
TVIS30003222
Fusion event
HIV-CD28 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
204595827/203731104 (Hg38)
End
204595827/203731104 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
CD28
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-145-5p
;
hsa-mir-574-5p
;
hsa-mir-6867-5p
;
hsa-mir-5586-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-2467-5p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-6832-3p
;
hsa-mir-6777-3p
;
hsa-mir-7107-3p
;
hsa-mir-6753-3p
;
hsa-mir-5089-5p
;
hsa-mir-6807-5p
;
hsa-mir-5589-5p
;
hsa-mir-4252
;
hsa-mir-4731-5p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-186-3p
;
hsa-mir-1273g-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-512-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
Nearest miRNA
hsa-mir-10b/Upstream/14597993; hsa-mir-1244-1/Downstream/3052130;
Nearest TSS
ENST00000437798/Upstream/24556;
ENST00000295854/Downstream/136682;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/195658
,
chr2-CpG: 83/Downstream/814112
Upstream sequence
GTTGTTCCCCACATGCTCCTTGCAGTTCAGAAGACCCTAGGGCTCAGATGGACATTTGTCAGGCTGCCTGTTGCTTACTCTGTACTTGCCGCAGGGTAGG
Downstream sequence
AAACAAAGTGGTTGCTTGTTCCTGGAAATTCTTTATACTAGGTATCATCTTAAGAATTTGCCTGGCTTGCCTTCTGCAAGTTGCCCAACCCTGAAGGTGG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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