Basic Information
VIS ID
TVIS30003223
Fusion event
HIV-ICOS integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
204814945/203950222 (Hg38)
End
204814945/203950222 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
ICOS
Nearest miRNA
hsa-mir-10b/Upstream/14817111; hsa-mir-1244-1/Downstream/2833012;
Nearest TSS
ENST00000437798/Upstream/13442; ENST00000411436/Downstream/140235;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/414776, chr2-CpG: 83/Downstream/594994
Upstream sequence
gagactgggtaatttataaagaaaagaaatgtatttcttacagttctggaggctggggcctaagtctaggggtctaggggcctaggtctaggctgaggcc
Downstream sequence
taggggcgaaatctggtgagggccttctttctggtggggacactcatcagaggcccaaggcagtacagaggattacatgatgaggaggttcttgagagac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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