Basic Information
VIS ID
TVIS30003224
Fusion event
HIV-ICOS integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.2
Reference genome
GRCh37/hg19
Start
204815000/203950277 (Hg38)
End
204815000/203950277 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
ICOS
Nearest miRNA
hsa-mir-10b/Upstream/14817166; hsa-mir-1244-1/Downstream/2832957;
Nearest TSS
ENST00000437798/Upstream/13497; ENST00000411436/Downstream/140180;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/414831, chr2-CpG: 83/Downstream/594939
Upstream sequence
gggcctaagtctaggggtctaggggcctaggtctaggctgaggcctaggggcgaaatctggtgagggccttctttctggtggggacactcatcagaggcc
Downstream sequence
caaggcagtacagaggattacatgatgaggaggttcttgagagacagccaatctggctgtttataacatactaactctcatgataattaacccactcctg
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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