Basic Information
VIS ID
TVIS30003368
Fusion event
HIV-DGCR2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
19105199/19117686 (Hg38)
End
19105199/19117686 (Hg38)
Orient
-
Location type
Intronic
Target gene
DGCR2
miRNAs that regulate target gene
hsa-mir-346 ; hsa-mir-484 ; hsa-mir-23b-3p
Nearest miRNA
hsa-mir-3198-1/Upstream/1136725; hsa-let-7a-3/Downstream/846067;
Nearest TSS
ENST00000624155/Upstream/51782; ENST00000456035/Downstream/3843;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/87280, chr22-CpG: 115/Downstream/3869
Upstream sequence
gaaaaaagcaatgtgtgtgagtacacagatatgcacatacacatggaagatgagggataaggcaaataaggtaaaatgccaacagtagggaagcctcagc
Downstream sequence
aaaggatatgcaggtgttctctgcactcactttactcttgcaacttttccgggagtttgaaattatttccaaataaaaGTTTTCTTTTTGTCAAGAAAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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