Basic Information
VIS ID
TVIS30003370
Fusion event
HIV-UBE2L3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
21925543/21571254 (Hg38)
End
21925543/21571254 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBE2L3
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-423-5p ; hsa-mir-93-5p ; hsa-mir-125a-5p
Nearest miRNA
hsa-mir-1286/Upstream/536982; hsa-let-7a-3/Downstream/81727;
Nearest TSS
ENST00000624155/Upstream/3524; ENST00000425975/Downstream/58758;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/2828, chr22-CpG: 159/Downstream/57243
Upstream sequence
AATTTAGCATTGTTGGCTACAACCAGATTGTAACCATTGCTTCAATCAGGATGGGGAAATTGCTGCAAAAGCCAAAAGTGAAACCTTTATGTGTGGCTTA
Downstream sequence
GGCAACTGATTGCCATCTGATCATTTCTTTGCAGCTTCACACTGCACACATTTCCCCTAAGGGCCCTCCTGTTGAGTAGCTTCCCAGAAGGGCTTTTCTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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