Basic Information
VIS ID
TVIS30003381
Fusion event
HIV-THOC5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
29933119/29537130 (Hg38)
End
29933119/29537130 (Hg38)
Orient
-
Location type
Intronic
Target gene
THOC5
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-30a-3p ; hsa-let-7f-5p ; hsa-let-7b-5p ; hsa-mir-5089-5p ; hsa-mir-6842-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-4740-3p ; hsa-mir-6504-3p ; hsa-mir-7703 ; hsa-mir-6807-5p ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-1273g-3p ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-6863 ; hsa-mir-510-5p ; hsa-mir-1227-3p ; hsa-mir-1254 ; hsa-mir-3116 ; hsa-mir-3690 ; hsa-mir-4638-3p ; hsa-mir-508-5p ; hsa-mir-517a-3p ; hsa-mir-517b-3p ; hsa-mir-517c-3p ; hsa-mir-6501-3p ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p
Nearest miRNA
hsa-mir-1286/Upstream/1077182; hsa-let-7a-3/Downstream/469919;
Nearest TSS
ENST00000624155/Upstream/392; ENST00000403999/Downstream/2339;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/55877, chr22-CpG: 30/Downstream/16359
Upstream sequence
ggctttggatccatgtctcttgctctccagaggctctgtctgctCTGTAACCACTAGGGAATACACATGCCATCTTCTGCTCCATTTCTTGCTTGAGAGG
Downstream sequence
TAAGACCTAAAACTTTCACAAACATGGACTTAGCAGCTATATAACCCAAAAGAGGCCCATGGACTGGCCTGGTTAGCACAGGGTGGGAACAGATTCTGGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate