Basic Information
VIS ID
TVIS30003398
Fusion event
HIV-EIF3L integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
38279324/37883317 (Hg38)
End
38279324/37883317 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
EIF3L
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-769-3p ; hsa-mir-340-3p ; hsa-mir-320a ; hsa-mir-7-5p ; hsa-mir-19b-3p ; hsa-mir-665 ; hsa-mir-7150 ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-873-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-3914 ; hsa-mir-7851-3p ; hsa-mir-5197-5p ; hsa-mir-490-3p
Nearest miRNA
hsa-mir-1286/Upstream/35543; hsa-let-7a-3/Downstream/84246;
Nearest TSS
ENST00000624155/Upstream/5256; ENST00000460638/Downstream/3387;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/33643, chr22-CpG: 98/Downstream/22630
Upstream sequence
cccgggaggtggaggttgcagtgagccaagatcgtgccattgcactccagcctgggcaacaagagtgaaactccgtctcaaaaaaaaaaaaaaaaaaaaa
Downstream sequence
aCTTGCAtgatcccagcactttgggaggctgaggcaggcagatcacgaggtcaggagatcaagaccatcctggctaacacggtgaaaccctgtctctact
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate