Basic Information
VIS ID
TVIS30003408
Fusion event
HIV-SUN2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
39140137/38744132 (Hg38)
End
39140137/38744132 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
SUN2
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-103a-3p ; hsa-mir-1226-3p ; hsa-mir-222-3p ; hsa-mir-30c-5p ; hsa-mir-27a-3p ; hsa-mir-3660 ; hsa-mir-6808-3p ; hsa-mir-4671-3p ; hsa-mir-3944-5p ; hsa-mir-4504 ; hsa-mir-4768-3p ; hsa-mir-4310 ; hsa-mir-7157-5p ; hsa-mir-454-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130a-3p ; hsa-mir-548b-3p ; hsa-mir-107 ; hsa-mir-758-3p ; hsa-mir-542-3p ; hsa-mir-5581-3p ; hsa-mir-7106-3p ; hsa-mir-4778-3p ; hsa-mir-4286 ; hsa-mir-6840-3p ; hsa-mir-6872-3p ; hsa-mir-665 ; hsa-mir-6777-3p ; hsa-mir-4433a-3p ; hsa-mir-335-5p
Nearest miRNA
hsa-mir-1286/Upstream/755279; hsa-let-7a-3/Downstream/2069751;
Nearest TSS
ENST00000624155/Upstream/637; ENST00000450216/Downstream/6182;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/37469, chr22-CpG: 132/Downstream/11320
Upstream sequence
gagacagagaccatcctggccaacatggtgaaaccctgtctctactaaaaataaaaaaattagctggcatggtggtgcgcgcctgtagtcccagctactc
Downstream sequence
gggacgctgaggcgggagaatcgcttgaacccgggaggtgtaggctgcagtgagcccagatcgtgccactgcactccagcctgggtgacgcagcattcca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate