Basic Information
VIS ID
TVIS30003428
Fusion event
HIV-SLC25A17 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41191020/40795016 (Hg38)
End
41191020/40795016 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
SLC25A17
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-mir-526b-5p ; hsa-mir-642a-5p ; hsa-mir-766-5p ; hsa-mir-4469 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4496
Nearest miRNA
hsa-mir-1286/Upstream/2806163; hsa-let-7a-3/Downstream/18867;
Nearest TSS
ENST00000624155/Upstream/14761; ENST00000614001/Downstream/24300;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/5604, chr22-CpG: 43/Downstream/24115
Upstream sequence
ccTAttttttaatatttttagagacggagtctcactatgttacccaggctggtctcaaacttgtgggctcaagggatcctcatgcctcagcctcccaaag
Downstream sequence
tgctgggattacaggcgtgagccaccatacccggccCGTGTATGTTTAAACTAAATCCTTTGAGGATTATAATTGTTAACATCAGCAAGTTTCACTGAAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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