Basic Information
VIS ID
TVIS30003555
Fusion event
HIV-TOMM70 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
100087515/100368671 (Hg38)
End
100087515/100368671 (Hg38)
Orient
-
Location type
Intronic
Target gene
TOMM70
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-342-3p ; hsa-mir-5698 ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-5693 ; hsa-mir-6499-3p ; hsa-mir-431-5p ; hsa-mir-193a-5p ; hsa-mir-7704 ; hsa-mir-615-5p ; hsa-mir-3665 ; hsa-mir-764 ; hsa-mir-6890-5p
Nearest miRNA
hsa-let-7g/Upstream/404273; hsa-mir-12124/Downstream/3155362;
Nearest TSS
ENST00000440867/Upstream/29577; ENST00000466996/Downstream/5054;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/33562, chr3-CpG: 102/Downstream/31989
Upstream sequence
tttctttctttttgttttttttgggacagagcctcactctgccgcccaggctggagagcagtggtgcaatcttggctcactgcaacctctgcctcccagg
Downstream sequence
ttcaagtgattctcactccttagcctgctgagtagctgggaatcgggcatgtgccaccacacctggctaattttttgtagttttagtagacaccgggttt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate