Basic Information
VIS ID
TVIS30003600
Fusion event
HIV-OPA1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
193350802/193633013 (Hg38)
End
193350802/193633013 (Hg38)
Orient
-
Location type
Intronic
Target gene
OPA1
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-320a ; hsa-mir-34a-5p
Nearest miRNA
hsa-let-7g/Upstream/3803004; hsa-mir-3137/Downstream/1501493;
Nearest TSS
ENST00000440867/Upstream/5676; ENST00000475899/Downstream/4203;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/39614, chr3-CpG: 52/Downstream/236550
Upstream sequence
AAAGTGAAACGACTAcaagttgaatatctcttatctgaggtgcttggggccagcgtgttttggatttcagatttttGAATTAGGGATAATCAGTCAGTAG
Downstream sequence
TATGTTTTGAGTCACAGGTTTCTTTGGTATCTATTTATTGAGTCTCAAACCTCACTATACGCTAGACTCACCTGTGctctgagtggcactatatctatgt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate