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Viral Integration Site DataBase
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TVIS30003644
Basic Information
VIS ID
TVIS30003644
Fusion event
HIV-RHOH integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
40193184/40191564 (Hg38)
End
40193184/40191564 (Hg38)
Orient
-
Location type
Intronic
Target gene
RHOH
miRNAs that regulate target gene
hsa-mir-9-5p
;
hsa-mir-4701-5p
;
hsa-mir-4715-3p
;
hsa-mir-4775
;
hsa-mir-1227-3p
;
hsa-mir-4735-5p
;
hsa-mir-500b-3p
;
hsa-mir-455-5p
;
hsa-mir-590-3p
;
hsa-mir-6807-5p
;
hsa-mir-6778-3p
;
hsa-mir-150-5p
;
hsa-mir-6787-3p
;
hsa-mir-6827-3p
;
hsa-mir-340-3p
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-6873-3p
;
hsa-mir-421
;
hsa-mir-505-3p
;
hsa-mir-7159-5p
;
hsa-mir-676-5p
;
hsa-mir-6515-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-3065-5p
;
hsa-mir-365a-3p
Nearest miRNA
hsa-mir-12113/Upstream/779590; hsa-mir-1243/Downstream/310476;
Nearest TSS
ENST00000502981/Upstream/511;
ENST00000514143/Downstream/1403;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/134300
,
chr4-CpG: 118/Downstream/246240
Upstream sequence
tttgactcatgtctgtgatgttgcaaaagcgcatcaactatcgagggactgctttgaagggaaacggtcatttgactacatttgctctgctctgacagac
Downstream sequence
tttttagaaaaagttgtatcataactttagagccacagcttgaatTATTACTTTGGGTGCTATCATCTTCCGCAACAAGACTCTGTCTTCTTATGAATTA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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