Basic Information
VIS ID
TVIS30003650
Fusion event
HIV-POLR2B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
57856068/56989902 (Hg38)
End
57856068/56989902 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4B
Target gene
POLR2B
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-30a-5p ; hsa-mir-455-3p ; hsa-mir-615-3p
Nearest miRNA
hsa-mir-12113/Upstream/4277155; hsa-mir-1243/Downstream/3932717;
Nearest TSS
ENST00000502981/Upstream/3493; ENST00000510355/Downstream/19657;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/10866, chr4-CpG: 124/Downstream/119792
Upstream sequence
TGTCCCTGGATGGTAATAGGGAGTGATCTGTTGAGATCCTCTTGCACGTGTATCTACTTGTCTCTGTATGTCTTTCCCCACCCCTCACCTGAAAAGTATC
Downstream sequence
TGTTCCTTATAAATATGATGTCTGCTTTTTAGATTGCAGCTCTCTCAGCCATGCTGCATTTTTATCACCAGTCTTTTGCTGAGTATTTTTATGTAAAGAC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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