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Viral Integration Site DataBase
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TVIS30003668
Basic Information
VIS ID
TVIS30003668
Fusion event
HIV-AFF1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
87922102/87000950 (Hg38)
End
87922102/87000950 (Hg38)
Orient
+
Location type
Intronic
Target gene
AFF1
miRNAs that regulate target gene
hsa-mir-128b
;
hsa-mir-877-5p
;
hsa-mir-615-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-142-3p
;
hsa-mir-6073
;
hsa-mir-1914-5p
;
hsa-mir-587
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-885-3p
;
hsa-mir-5197-5p
;
hsa-mir-205-5p
;
hsa-mir-1228-3p
;
hsa-mir-519e-3p
;
hsa-mir-515-3p
;
hsa-mir-33b-3p
;
hsa-mir-371a-3p
;
hsa-mir-371b-3p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-4279
;
hsa-mir-361-5p
;
hsa-mir-889-3p
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-1324
;
hsa-mir-2115-3p
;
hsa-mir-3074-3p
;
hsa-mir-5571-5p
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-4744
;
hsa-mir-1273h-3p
;
hsa-mir-143-5p
;
hsa-mir-3944-5p
;
hsa-mir-5093
;
hsa-mir-4480
;
hsa-mir-3166
;
hsa-mir-4771
;
hsa-mir-6790-3p
;
hsa-mir-3691-3p
;
hsa-mir-548an
;
hsa-mir-31-5p
;
hsa-mir-5684
;
hsa-mir-4511
;
hsa-mir-548b-3p
;
hsa-mir-5692b
;
hsa-mir-5692c
Nearest miRNA
hsa-mir-12113/Upstream/458398; hsa-mir-1243/Downstream/299545;
Nearest TSS
ENST00000502981/Upstream/64540;
ENST00000511722/Downstream/6038;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/64898
,
chr4-CpG: 76/Downstream/5826
Nearest cancer related gene
AFF1
(OG, No orient, 0)
Upstream sequence
tgtatacatttttgcttgtatacctcctacaagaatgttgaaaaactgtAaatctttattcttgaaccaaacagttgaatcagatttattttattagaga
Downstream sequence
aagtctaacttcTGATGGCCCTATACATCTCATTTCATAATTCTAATTTGTATATAGTCAGGCATAGGCACCTTGCCGCAGGCTTGTTACCTGGATGTGT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Sample Information
×
Sample name
Active CD4+
Sample type
Cell line
Gender
Female
CpG Island Information
×
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