Basic Information
VIS ID
TVIS30003680
Fusion event
HIV-EGF integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
110898395/109977239 (Hg38)
End
110898395/109977239 (Hg38)
Orient
+
Location type
Intronic
Target gene
EGF
miRNAs that regulate target gene
hsa-mir-1304-5p ; hsa-mir-1273e ; hsa-mir-6765-5p ; hsa-mir-6807-5p ; hsa-mir-6894-5p ; hsa-mir-4722-5p ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-1827 ; hsa-mir-1233-3p ; hsa-mir-1225-3p ; hsa-mir-4649-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-223-5p
Nearest miRNA
hsa-mir-12113/Upstream/488444; hsa-mir-1243/Downstream/883343;
Nearest TSS
ENST00000502981/Upstream/1152; ENST00000511228/Downstream/3402;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/247147, chr4-CpG: 80/Downstream/219067
Upstream sequence
gaggattttgtaacagattgcatatagaaaatgagagccagggaagtgttgaagatgCTTTGGAGAGTTAGAAATTGGTTGGGAAGATGAAAAAACATGG
Downstream sequence
TTTCTCTCATTTAGGAAGAAGCTAACCAACTAATAATCTGTATAAGATACCTATTTTGCCCATTCTCTTTGGCTTAAGATAAGtataatttaaaatttta
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate