Basic Information
VIS ID
TVIS30003686
Fusion event
HIV-PDE5A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q26
Reference genome
GRCh37/hg19
Start
120486775/119565620 (Hg38)
End
120486775/119565620 (Hg38)
Orient
-
Location type
Intronic
Target gene
PDE5A
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-570-3p ; hsa-mir-944 ; hsa-mir-5692a ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac
Nearest miRNA
hsa-mir-12113/Upstream/4908766; hsa-mir-1305/Downstream/5941639;
Nearest TSS
ENST00000502981/Upstream/2648; ENST00000505122/Downstream/62013;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/110412, chr4-CpG: 143/Downstream/61428
Upstream sequence
TTTGTTCTACATAAAATTAGGATGATATAAACTAAGTCTTAGCTAAAGGTATTGGAATAGTCTCCTAAGGTATAAATTAGGTATAAATCAATAAGGAGAA
Downstream sequence
AAAGGAGAGGAACTAAGATAAAGACTTTATCTCTTTATACCACTTGAAGTTACAATTTATTCCATGCAAAATTTGGTTTAGCCTCTCCATGATATTAAGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate