Basic Information
VIS ID
TVIS30003700
Fusion event
HIV-MARCH1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
164634556/163713404 (Hg38)
End
164634556/163713404 (Hg38)
Orient
-
Location type
Intronic
Target gene
MARCH1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-4446-5p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-337-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-8068 ; hsa-mir-5087 ; hsa-mir-6832-3p ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-202-5p
Nearest miRNA
hsa-mir-12113/Upstream/619776; hsa-mir-1305/Downstream/1672838;
Nearest TSS
ENST00000502981/Upstream/99870; ENST00000515485/Downstream/140774;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/218370, chr4-CpG: 36/Downstream/474878
Upstream sequence
AATTATTACTTCATATAGTATTCTACTAATAAATAAAAAATTTGCCATAATGcctgggtccaaatcccaactataccacttgtggtgcaatcctaggcaa
Downstream sequence
gttacttattcactcatgacttctgtttatgcatctgtagaatcatgataatagtacagtcctctcaatgttgctgtaagaattaaataagtaaatggga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate