Basic Information
VIS ID
TVIS30003714
Fusion event
HIV-WDR70 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
37483376/37483274 (Hg38)
End
37483376/37483274 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
WDR70
miRNAs that regulate target gene
hsa-mir-6844 ; hsa-mir-6873-3p ; hsa-mir-9-5p ; hsa-mir-4778-3p ; hsa-mir-7152-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-660-3p ; hsa-mir-5193
Nearest miRNA
hsa-mir-10397/Upstream/1335286; hsa-mir-103a-1/Downstream/1074228;
Nearest TSS
ENST00000502646/Upstream/3804; ENST00000508730/Downstream/239369;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/103720, chr5-CpG: 51/Downstream/351295
Upstream sequence
caatagtggagggaagatcagcagataaacaagtgaacaaaggtctctggttttcctaggcagaggaccctgcggccttccgcagtgtttgtgtccctgg
Downstream sequence
gtacttgagattagggagtggtgatgactcttaacgagcatgctgccttcaagcatctgtttaacaaagcacatcttgcaccgcccttaatccatttaac
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate