Basic Information
VIS ID
TVIS30003717
Fusion event
HIV-PARP8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
49969897/50674063 (Hg38)
End
49969897/50674063 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5H
Target gene
PARP8
miRNAs that regulate target gene
hsa-mir-145-5p
Nearest miRNA
hsa-mir-10397/Upstream/12116502; hsa-mir-103a-1/Downstream/3277441;
Nearest TSS
ENST00000502646/Upstream/6170; ENST00000508923/Downstream/185957;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/6120, chr5-CpG: 53/Downstream/295188
Upstream sequence
ATAGCTGCCACTGATTATTTTAGTCTATTTTAATCAACTTATTGCCTTGTAATCTTTCCTTTTTCATTCTCTAAATTTCTGAAATTCCATCTTTCGTGTT
Downstream sequence
CCCCAGGAAAGACTAGTAAGATGTGTTTTTATTAACAAGACTTACTATCCTCATTTCACCATGACATAAGTTGGGCTTTCTGTTCCAATTTATCCTACTT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate