Basic Information
VIS ID
TVIS30003722
Fusion event
HIV-MAP3K1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
56179502/56883675 (Hg38)
End
56179502/56883675 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
FRA5H
Target gene
MAP3K1
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-423-3p ; hsa-mir-125a-5p ; hsa-let-7g-5p ; hsa-mir-34a-5p ; hsa-let-7a-5p ; hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-153-5p ; hsa-mir-3646 ; hsa-mir-4762-3p ; hsa-mir-4539 ; hsa-mir-1252-3p ; hsa-mir-5585-3p ; hsa-mir-4703-3p ; hsa-mir-509-3p ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-323a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-451a
Nearest miRNA
hsa-mir-10397/Upstream/1374749; hsa-mir-103a-1/Downstream/1646368;
Nearest TSS
ENST00000502646/Upstream/21511; ENST00000469188/Downstream/2278;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/66593, chr5-CpG: 113/Downstream/25460
Upstream sequence
AAGACACTGAATGGCTGAAAGGTCAACAGATAGGCCTTGGAGCATTTTCTTCTTGTTATCAGGCTCAAGATGTGGGAACTGGAACTTTAATGGCTGTTAA
Downstream sequence
ACAGGTAAATATCTAGTGAGCATATAAATGAAATGACTCAAATCACAAAATGAAGCATGTTCAGTAAAAAGAATAAAGGATATGTCCACGTGTGTGTACT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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