Basic Information
VIS ID
TVIS30003739
Fusion event
HIV-FBXL17 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
107527543/108191842 (Hg38)
End
107527543/108191842 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
FBXL17
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-186-3p ; hsa-mir-548p ; hsa-mir-548b-3p ; hsa-mir-330-3p
Nearest miRNA
hsa-mir-10397/Upstream/7375277; hsa-mir-103a-1/Downstream/2321987;
Nearest TSS
ENST00000502646/Upstream/475001; ENST00000513676/Downstream/172925;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/519352, chr5-CpG: 220/Downstream/188766
Upstream sequence
CACTGGGATACTTGTGACTCTTACTGCCTGTATGTACTGTCCATAAATAAAACATTTCTCACTCTTCCAGTGGAGCACAAATGTATACATGAAGAAACAG
Downstream sequence
GTTTACTTGAGCTCTTATGCTCCAGGCTTCTACAGCAACCTTAAAGAGTATTTTACTTTTCTTTTTTCATGAGCTGACAGTCACTGCATTCACATGGCCT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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