Basic Information
VIS ID
TVIS30003760
Fusion event
HIV-KLHL3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
137061908/137726219 (Hg38)
End
137061908/137726219 (Hg38)
Orient
+
Location type
Intronic
Target gene
KLHL3
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-92a-3p ; hsa-mir-6715b-3p ; hsa-mir-4635 ; hsa-mir-7705 ; hsa-mir-6854-5p ; hsa-mir-382-5p ; hsa-mir-595 ; hsa-mir-3941 ; hsa-mir-3618 ; hsa-mir-601 ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-7113-5p ; hsa-mir-1182 ; hsa-mir-508-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-7107-3p ; hsa-mir-6753-3p ; hsa-mir-5701 ; hsa-mir-4742-3p ; hsa-mir-7153-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1254 ; hsa-mir-186-3p ; hsa-mir-18a-5p ; hsa-mir-18b-5p ; hsa-mir-3116 ; hsa-mir-4450 ; hsa-mir-4667-5p ; hsa-mir-4700-5p ; hsa-mir-4735-3p ; hsa-mir-661 ; hsa-mir-6852-5p ; hsa-mir-6857-5p ; hsa-mir-6882-3p ; hsa-mir-8089
Nearest miRNA
hsa-mir-10397/Upstream/78570; hsa-mir-103a-1/Downstream/2837452;
Nearest TSS
ENST00000502646/Upstream/4909; ENST00000604680/Downstream/9639;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/226762, chr5-CpG: 168/Downstream/27225
Upstream sequence
TTTCAGATCCTCACTGCACACAGGTCTCTTCGGGGCTGTGAGGTTTATGAGCTGAAgcttcagtcacagccctctgcctccatttgttctatatgttgag
Downstream sequence
ggtccacataaaatttcctttcaaAGGACTCTATAGCTAAAAAGCTGAAAAATCATCAGTCTACAGGATAAAGTCATGATTCTTGACTAGTATTCAAGGA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate