Basic Information
VIS ID
TVIS30003777
Fusion event
HIV-RNF145 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
158629746/159202738 (Hg38)
End
158629746/159202738 (Hg38)
Orient
+
Location type
Intronic
Target gene
RNF145
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-331-3p ; hsa-mir-17-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-513b-5p ; hsa-mir-7160-5p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-7162-3p ; hsa-mir-4719
Nearest miRNA
hsa-mir-10397/Upstream/4373198; hsa-mir-103a-1/Downstream/1271664;
Nearest TSS
ENST00000502646/Upstream/28697; ENST00000520323/Downstream/4896;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/95746, chr5-CpG: 86/Downstream/6406
Upstream sequence
CAGGCAACTCTAATAATAAAATATTAGCAAAACCACTATAGTACCATTCAAACCATGTCTGGAACTCTGCAATCACAACATTAATAAAATATATTGCTAT
Downstream sequence
ATACATTACAAATAAACCAAAACCTAAAAAGTAAGGATCATGATTTTTATTCTAGGTAAATTTTATCTGTTTCATGCTTGTATTTCTTGACTTTAATTTC
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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