Basic Information
VIS ID
TVIS30003794
Fusion event
HIV-HIVEP1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
12054316/12054083 (Hg38)
End
12054316/12054083 (Hg38)
Orient
-
Location type
Intronic
Target gene
HIVEP1
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-98-5p ; hsa-mir-32-5p ; hsa-mir-23a-3p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-433-3p ; hsa-mir-92b-3p ; hsa-mir-1206 ; hsa-mir-7154-5p ; hsa-mir-595 ; hsa-mir-410-3p ; hsa-mir-3613-3p ; hsa-mir-190a-3p ; hsa-mir-3163 ; hsa-mir-548e-5p
Nearest miRNA
hsa-mir-3691/Upstream/1614289; hsa-mir-10398/Downstream/4087473;
Nearest TSS
ENST00000381078/Upstream/38496; ENST00000399469/Downstream/71663;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/41249, chr6-CpG: 44/Downstream/695562
Nearest cancer related gene
HIVEP1(TSG, No orient, 0)
Upstream sequence
CTTGTTAGTATCAGAAACGTAGGTTATCTTTCCCTTCTCCATTTCAAATAGTCTGTCATATTTGAAAGCTAATAGCTTTCAGGCTCGCATTGCCCATAAC
Downstream sequence
TCTCAGCAACATATAAAACATGCCCACTCTGTGTTTATTTACTTTAATCTGTCAATTGTGATGCCAACTCAAGATATTTGGGATTATTACATTTGATTCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate