Basic Information
VIS ID
TVIS30003912
Fusion event
HIV-USP45 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q16.2
Reference genome
GRCh37/hg19
Start
99951820/99503944 (Hg38)
End
99951820/99503944 (Hg38)
Orient
-
Location type
Intronic
Target gene
USP45
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-32-5p ; hsa-let-7f-5p ; hsa-mir-4777-5p ; hsa-mir-3149 ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-630 ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-3145-3p ; hsa-mir-520g-5p ; hsa-mir-6783-5p ; hsa-mir-6873-5p ; hsa-mir-3662 ; hsa-mir-665
Nearest miRNA
hsa-mir-10398/Upstream/379248; hsa-mir-1202/Downstream/7280181;
Nearest TSS
ENST00000381078/Upstream/171; ENST00000636394/Downstream/4837;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/78614, chr6-CpG: 67/Downstream/11133
Upstream sequence
TTTTCATCACATTCATAACACCTGAAAAAGTATAAAATTTAAGAAAATATTATGAAAATATTCTCAATAATTTTGCACATCAGATAACAAAGTTGGTATT
Downstream sequence
TAGTTACTTTTGTCTTTAAATTACATGggagggaatacaaaggggaagccaccaggtaagtctagagaaataagcagaggacaattcatacagagactta
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate