Basic Information
VIS ID
TVIS30003928
Fusion event
HIV-MAP3K5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
137054520/136733382 (Hg38)
End
137054520/136733382 (Hg38)
Orient
+
Location type
Intronic
Target gene
MAP3K5
miRNAs that regulate target gene
hsa-mir-769-3p ; hsa-mir-20a-5p ; hsa-mir-218-5p ; hsa-mir-1303 ; hsa-mir-5191 ; hsa-mir-4753-3p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-130b-5p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-4517 ; hsa-mir-425-5p ; hsa-mir-301a-3p ; hsa-mir-19a-3p ; hsa-mir-1224-3p ; hsa-mir-4775 ; hsa-mir-590-3p
Nearest miRNA
hsa-mir-10398/Upstream/1494126; hsa-mir-1202/Downstream/1701831;
Nearest TSS
ENST00000381078/Upstream/104210; ENST00000367756/Downstream/59136;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/182375, chr6-CpG: 172/Downstream/58156
Upstream sequence
ccaccacgtccagcTTCAAGCACACAGCATTCGATGATGGTTTAGTAAGTGCTATTGAGGGAGCCCTGCAAATACTGTCACTGGGTTGTCTTCAAGTGAA
Downstream sequence
TCCCTCATATCACTTCACAAAAAAAGTGGGTAAATCACAGTTTATATCTTCTGGTGCATACCAAGTACTTTATGAAGAGATATTTTCCTGATATGAGCAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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