Basic Information
VIS ID
TVIS30003931
Fusion event
HIV-HECA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
139475541/139154404 (Hg38)
End
139475541/139154404 (Hg38)
Orient
-
Location type
Intronic
Target gene
HECA
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-5787 ; hsa-mir-6884-5p ; hsa-mir-4505 ; hsa-mir-485-5p
Nearest miRNA
hsa-mir-10398/Upstream/719110; hsa-mir-1202/Downstream/1050848;
Nearest TSS
ENST00000381078/Upstream/19292; ENST00000441249/Downstream/84898;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/18425, chr6-CpG: 16/Downstream/12618
Nearest cancer related gene
HECA(TSG, No orient, 0)
Upstream sequence
ATATGAATGGGGTGGAGAGGGAGTCTTAGCTACCTGGAGAATGTGTGCTGCACCAAAACAGCATTCTGATTCACATTCCAAAAAAAAACTCTGGACTGGT
Downstream sequence
TTACTAAGACACAATGCAGGCCAAACTGCCCCATTGGAACTCTGATCTAGGGGATATATAGACATCatatcacctattatcagttgagcttttagaatat
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate