Basic Information
VIS ID
TVIS30003981
Fusion event
HIV-COA1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
43670000/43630401 (Hg38)
End
43670000/43630401 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
COA1
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-17-5p ; hsa-mir-218-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-6077 ; hsa-mir-6783-5p ; hsa-mir-6859-5p ; hsa-mir-3916 ; hsa-mir-3125 ; hsa-mir-651-3p
Nearest miRNA
hsa-mir-1183/Upstream/479407; hsa-mir-10399/Downstream/421365;
Nearest TSS
ENST00000635602/Upstream/8112; ENST00000453612/Downstream/11763;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/46608, chr7-CpG: 64/Downstream/98814
Nearby gene
STK17A(No orient, 3022)
Upstream sequence
CTTGCCATTTTTATTGAAATAAGTGGAGATTTTATTTACTAAAAATAAAACTATTTTTCCTAAATATGTTAGCAGCAGAAAAGTATCTCAGTTTCAATAC
Downstream sequence
ATTGTGATGGGTTTGCATGAAAATTAGTATCTCTTTAGTTATCTCAAGTAACCAGCTTTCTAATAAATTGTAAGAGAAGTATACCTAGAAGATAAAGTAT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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