Basic Information
VIS ID
TVIS30003990
Fusion event
HIV-IKZF1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
50365255/50325659 (Hg38)
End
50365255/50325659 (Hg38)
Orient
-
Location type
Intronic
Target gene
IKZF1
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1183/Upstream/5443859; hsa-mir-10399/Downstream/6630126;
Nearest TSS
ENST00000635602/Upstream/7253; ENST00000492119/Downstream/1720;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/20736, chr7-CpG: 79/Downstream/74209
Nearest cancer related gene
IKZF1(TSG, No orient, 0)
Upstream sequence
tcaggagatcgagaccatcttggctaacacggtgaaaccctgtctctactaaaaaaatacaaaaatttagttgggcatggtgggggatacctgtggtccc
Downstream sequence
agctactcgggaggctgagacaggagaatggcttgaacctgggaggccgagcttgcagtgagccaagatcgcgccactgcactccagcctgggtgacaga
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate