Basic Information
VIS ID
TVIS30004015
Fusion event
HIV-KMT2E integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
104698838/105058391 (Hg38)
End
104698838/105058391 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7F
Target gene
KMT2E
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-1301-3p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p
Nearest miRNA
hsa-mir-10525/Upstream/2586860; hsa-mir-10399/Downstream/9594954;
Nearest TSS
ENST00000635602/Upstream/20265; ENST00000485619/Downstream/3527;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/43872, chr7-CpG: 28/Downstream/186211
Upstream sequence
CATTAGGAGAGGCAAATAAAGCTTGGTTGTCTAACTCCTAATGATGATATTAATGATCAACAGATTCAGGTGTTGTCatcttatctacctatcaaccttc
Downstream sequence
tacctaagactcttagcatccatggttatttgttgcccagatatataacctcttaagggttgcagtttagttatttttctaatttatttattccttctgc
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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