Basic Information
VIS ID
TVIS30004072
Fusion event
HIV-ZDHHC2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
GRCh37/hg19
Start
17079303/17221794 (Hg38)
End
17079303/17221794 (Hg38)
Orient
-
Location type
UTR3
Target gene
ZDHHC2
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-541-5p ; hsa-mir-578 ; hsa-mir-4762-3p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-526b-5p ; hsa-mir-4303 ; hsa-mir-5186 ; hsa-mir-4635 ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-1279 ; hsa-mir-487a-3p ; hsa-mir-154-3p
Nearest miRNA
hsa-mir-124-1/Upstream/2368284; hsa-mir-10400/Downstream/459784;
Nearest TSS
ENST00000518652/Upstream/13781; ENST00000521005/Downstream/13066;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/64513, chr8-CpG: 73/Downstream/24761
Nearest cancer related gene
ZDHHC2(TSG, No orient, 0)
Upstream sequence
AACAATGTCAGCCAAGTCCATTTTATAGTTTGAGTGCAATTCTTTGAACAATAGAAATATCTGCAGTCTTTCACAGATTTGTATTATGCTGAAGAGTTTC
Downstream sequence
ATCTGACAATCTGCTTCAAGAAATCTCAGAAAATATGATAACATTTTAACTTTCATTTTAGAGCACGTTTTGGTCATTTTTAAAAATACCTAAAGTGCCA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate