Basic Information
VIS ID
TVIS30004105
Fusion event
HIV-PKIA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
79444846/78532611 (Hg38)
End
79444846/78532611 (Hg38)
Orient
+
Location type
Intronic
Target gene
PKIA
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-26b-5p ; hsa-mir-4684-5p ; hsa-mir-2113 ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-210-3p ; hsa-mir-147b ; hsa-mir-6844 ; hsa-mir-550a-3p ; hsa-mir-200c-5p ; hsa-mir-4762-5p ; hsa-mir-654-3p ; hsa-mir-6753-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-20a-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-6728-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-3679-3p ; hsa-mir-1283 ; hsa-mir-7849-3p ; hsa-mir-139-3p ; hsa-mir-6804-5p ; hsa-mir-4524a-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac
Nearest miRNA
hsa-mir-124-1/Upstream/1565761; hsa-mir-10400/Downstream/799577;
Nearest TSS
ENST00000518652/Upstream/16256; ENST00000518467/Downstream/25882;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/16092, chr8-CpG: 37/Downstream/133417
Upstream sequence
aaaaaaaaaaaaaaggaagaaaTTTTTCTGATTGGTCAGATTTAATTGAACATTCACTGAGCCATATTTTACTATTGCATCGGGTCACTGTGTATTTAAA
Downstream sequence
GATACAAAGCAggctggacgcagtggctcacacctatgtaatcccagcactttgggaggctaaggcaggcagatcacttaagaccaggagatcaagacca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate