Basic Information
VIS ID
TVIS30004110
Fusion event
HIV-IMPA1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
82588000/81675765 (Hg38)
End
82588000/81675765 (Hg38)
Orient
+
Location type
Intronic
Target gene
IMPA1
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-132-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-365a-3p ; hsa-mir-27a-3p ; hsa-mir-6504-3p ; hsa-mir-548aw ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-4252 ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-6889-3p ; hsa-mir-4438
Nearest miRNA
hsa-mir-12123/Upstream/1434292; hsa-mir-10400/Downstream/9529720;
Nearest TSS
ENST00000518652/Upstream/1344; ENST00000297265/Downstream/10067;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/44525, chr8-CpG: 41/Downstream/10267
Upstream sequence
TTAGTAACCATCCTTTACTGTTTGACCAACTAAGGAGCCAAACAGCAAGGAAATGCTATAGCTATATGTTTTATTCTGCTAGGCTTTAGATGTAAGTATT
Downstream sequence
TACACATAAGACAACCTGAACTATGTGTAGGTTCCTAAAGAGAGTCTGTATTTTCCAACCATGCTTTggcccctgctacttgctggtttctaaatgtatt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate