Basic Information
VIS ID
TVIS30004118
Fusion event
HIV-INTS8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
95888926/94876698 (Hg38)
End
95888926/94876698 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
INTS8
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-132-3p ; hsa-mir-128-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-340-5p ; hsa-mir-3163 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p
Nearest miRNA
hsa-mir-12123/Upstream/960579; hsa-mir-10400/Downstream/196213;
Nearest TSS
ENST00000518652/Upstream/747; ENST00000605911/Downstream/7911;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/52994, chr8-CpG: 209/Downstream/17862
Nearest cancer related gene
INTS8(OG, No orient, 0)
Upstream sequence
TTTTATTATCAGTGTTTACTTTATAAAAGATCCTTTTTTGATAATTTTAACTGTTCCATGTCATTATATattattttaaaatgttagatcatgtcatttc
Downstream sequence
tcagtcccaaactttccaatggcttctcatctcatacaaagttaaaagtcttacgatggctttataaggctatatacaacttgacctctagcctgtccgt
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate