Basic Information
VIS ID
TVIS30004127
Fusion event
HIV-FBXO32 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
124533522/123521282 (Hg38)
End
124533522/123521282 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
FBXO32
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-mir-608 ; hsa-mir-593-5p ; hsa-mir-541-5p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426
Nearest miRNA
hsa-mir-12123/Upstream/173152; hsa-mir-10400/Downstream/987233;
Nearest TSS
ENST00000518652/Upstream/14657; ENST00000518633/Downstream/10861;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/104097, chr8-CpG: 145/Downstream/19017
Nearest cancer related gene
FBXO32(TSG, No orient, 0)
Upstream sequence
aagacagcaagtgttgtcctgtttcccactctacccccagcttggcacatggtaagcactcaacaaatagtgttttttaaaACATACATTTGTCTTTTTg
Downstream sequence
aatcaaagagtgttgtagctggaagggactcaggaaacagtttacccgaatttcctcctgctatagatgaggtggctcatgatggccaaatgacacatca
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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