Basic Information
VIS ID
TVIS30004128
Fusion event
HIV-TMEM65 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
125328155/124315914 (Hg38)
End
125328155/124315914 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
TMEM65
miRNAs that regulate target gene
hsa-mir-33a-5p ; hsa-let-7b-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4733-5p ; hsa-mir-4695-5p ; hsa-mir-6736-5p ; hsa-mir-4701-3p ; hsa-mir-1262 ; hsa-mir-489-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-3913-3p ; hsa-mir-6776-5p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-4432 ; hsa-mir-1254 ; hsa-mir-1273g-3p ; hsa-mir-3116 ; hsa-mir-3613-3p ; hsa-mir-3690 ; hsa-mir-371a-5p ; hsa-mir-371b-5p ; hsa-mir-372-5p ; hsa-mir-373-5p ; hsa-mir-451b ; hsa-mir-4638-3p ; hsa-mir-4668-5p ; hsa-mir-4696 ; hsa-mir-4793-3p ; hsa-mir-616-5p ; hsa-mir-6501-3p ; hsa-mir-7703
Nearest miRNA
hsa-mir-12123/Upstream/967784; hsa-mir-10400/Downstream/192601;
Nearest TSS
ENST00000518652/Upstream/44231; ENST00000522518/Downstream/56778;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/14058, chr8-CpG: 132/Downstream/55662
Upstream sequence
CAGAGTTTTAACAAGAAGAAATTTTCTTCATTCCACATGCTGATAAAGTTAATCCTAGCTTCTTGTTTTTTGACTTTAACATATTTACTCATTTGAATAT
Downstream sequence
ATGCATAGAGAAATCATTATATTCTATTTCAGACTCCTGACTTTCCCATATACAGAAAATAACCATTGCCAATAGGCCCCACTTTCACTTCCCACCCATT
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate