Basic Information
VIS ID
TVIS30004196
Fusion event
HIV-ASTN2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
119951528/117189249 (Hg38)
End
119951528/117189249 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA9E ; FRA9B
Target gene
ASTN2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-526b-5p ; hsa-mir-1253 ; hsa-mir-591 ; hsa-mir-6761-5p ; hsa-mir-5571-5p ; hsa-mir-6880-5p ; hsa-mir-8085 ; hsa-mir-6746-5p ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-6077 ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6760-5p ; hsa-mir-4419a ; hsa-mir-4779 ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6770-5p ; hsa-mir-124-5p ; hsa-mir-6867-5p ; hsa-mir-5195-5p ; hsa-mir-8485 ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-3152-3p ; hsa-mir-1251-3p
Nearest miRNA
hsa-let-7a-1/Upstream/2979720; hsa-mir-12126/Downstream/3055730;
Nearest TSS
ENST00000422679/Upstream/501906; ENST00000450938/Downstream/25304;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/501761, chr9-CpG: 163/Downstream/223726
Upstream sequence
GAAAGAAAACAACGGCACTTAAAAGTGCTCAGGAGATAGGATCAGGAGAACTGCTGTTTACCCACTACCCACTAGGCAGCAAATTAGTCCCTTCCAGTCA
Downstream sequence
GGGATATATTCATTTGCCCATTCACCCATTCATTTTAAACATATTTAGCAATCTCCTATGATGAGTCAAGACAAAGGCATGGGCTGGAACATGGATAGAA
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate