Basic Information
VIS ID
TVIS30004216
Fusion event
HIV-LRRC8A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.11
Reference genome
GRCh37/hg19
Start
131657605/128895326 (Hg38)
End
131657605/128895326 (Hg38)
Orient
+
Location type
Intronic
Target gene
LRRC8A
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-33a-5p ; hsa-let-7b-5p ; hsa-mir-149-5p ; hsa-let-7e-5p ; hsa-mir-191-5p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-1250-3p ; hsa-mir-330-3p ; hsa-mir-6715a-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-4804-5p ; hsa-mir-184 ; hsa-mir-4719 ; hsa-mir-4694-3p
Nearest miRNA
hsa-let-7a-1/Upstream/502612; hsa-mir-12126/Downstream/974279;
Nearest TSS
ENST00000422679/Upstream/10331; ENST00000492784/Downstream/17418;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/12856, chr9-CpG: 80/Downstream/12277
Upstream sequence
AAGTTGTAGAAGctcgggaggctgaggtaggagaatcacttgaacccgggaggtggaggttgcagtgagccaagaccgtgccactgcactccagcctggg
Downstream sequence
ccacggagcaaagcaagactgtctccaagataaaataaaataaGTTGTAAaagcagaggcttaggctaaacaatttgcctggggtcacagaattatttct
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate