Basic Information
VIS ID
TVIS30004274
Fusion event
HIV-HUWE1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
53690784/53663830 (Hg38)
End
53690784/53663830 (Hg38)
Orient
-
Location type
Intronic
Target gene
HUWE1
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-1303 ; hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-424-3p ; hsa-mir-7-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-93-3p ; hsa-mir-660-5p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-324-3p ; hsa-mir-361-5p ; hsa-mir-29c-3p ; hsa-mir-106b-5p ; hsa-mir-320a ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-125b-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-196a-5p ; hsa-mir-93-5p ; hsa-mir-29a-3p ; hsa-mir-17-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6826-3p ; hsa-mir-190a-3p ; hsa-mir-4775 ; hsa-mir-3613-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-590-3p ; hsa-mir-1277-5p ; hsa-mir-542-5p
Nearest miRNA
hsa-let-7f-2/Upstream/106556; hsa-mir-105-1/Downstream/1787665;
Nearest TSS
ENST00000429181/Upstream/9723; ENST00000375151/Downstream/20339;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/221754, chrX-CpG: 89/Downstream/19729
Upstream sequence
TTTGAACAGAATGATATCCAGAATTTGGACAATCTTCTCCCGAACCCCTCAAATCTTGACTGGATATCCCACCATATGTGATTACATTGTACTCTGTACC
Downstream sequence
TATCACTTCCCTATTTATGAGAAAATGTCTGCCACAGGGTGGGAAAGTTAAAAAAAAAAAAAAACCTGGGAAGGGAAGAAATACACATTATTAGTAGTTG
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
Curate