Basic Information
VIS ID
TVIS30004287
Fusion event
HIV-DIAPH2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2013
PubMed ID
23953889
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
96089104/96834105 (Hg38)
End
96089104/96834105 (Hg38)
Orient
+
Location type
Intronic
Target gene
DIAPH2
miRNAs that regulate target gene
hsa-mir-10b-5p ; hsa-mir-17-3p ; hsa-mir-4520-3p ; hsa-mir-4520-2-3p ; hsa-mir-20a-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4473 ; hsa-mir-4671-3p ; hsa-mir-4778-3p ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-512-3p ; hsa-mir-641 ; hsa-mir-3617-5p
Nearest miRNA
hsa-let-7f-2/Upstream/1770879; hsa-mir-105-1/Downstream/9805709;
Nearest TSS
ENST00000429181/Upstream/149088; ENST00000373040/Downstream/49803;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/148738, chrX-CpG: 23/Downstream/3105231
Upstream sequence
TTTGTATCTCACATTCTTGCATGATCATATTTAAGACAACAGGATTTGTTCAACATTCCTAGACACCTAGTATGTCAAGGAATGTTTCTACATAAGTATT
Downstream sequence
ATTTATTGAAATAAGCTGCATTTAGACTATGCTACTCACCATATAAaggttgactatgcctaatccaaacatctgaaatctgcaatactccaaaCctaaa
Reference
Sherrill-Mix, S., et al. HIV latency and integration site placement in five cell-based models.2013, Retrovirology 10: 90.
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